CircuGuard
CircuGuard
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Formula Purposes & Benefits |
CircuGuard is formulated to support healthy blood flow and reduce clotting factors. Designed using the mechanisms of action found in Triple Anticoagulant Therapy (1), CircuGuard’s all-natural Organic Turmeric Root Extract, White Willow Extract, and Dan Shen ingredients help support a health cardiovascular and circulatory system in people recovering from the adverse effects of Long Covid, microclots, and platelet hyperactivation. The active ingredient in Black Pepper Root extract, piperine, boosts the bioavailability and duration of action of Turmeric. (6) The ingredients in CircuGuard are also powerful anti-inflammatory (White Willow extract, Turmeric, Dan Shen, and Beet Root extract) and antioxidant (Turmeric, Dan Shen, and Beet Root extract) agents. Our CircuGuard formula is completely unique and innovative formula to support people with Long Covid on their road to recovery. |
Formula Ingredient Deck |
Benefits Of Each Ingredient |
Organic Turmeric Root Extract (Curcumin 95%) |
● The curcumin active ingredient in Turmeric acts as an anticoagulant, helping to prevent the formation of blood clots. (2) ● The mechanism of action for curcumin as an anticoagulant is inhibition of activated Factor X (FXa) and inhibition of thrombin. (2) ● Turmeric is a powerful anti-inflammatory and antioxidant. (2) |
White Willow Extract (std. 15% Salicin) |
● White Willow Extract acts as a platelet activation inhibitor, preventing platelets from contributing to clot formation. (3) ● Salicin, the active ingredient in White Willow Extract, inhibits platelet activation by inhibiting the COX-1 enzyme (mechanism of action). (3) ● White Willow Extract, and it’s salicin active ingredient, also act as an anti-inflammatory by inhibiting the COX-2 enzyme. (3) |
Dan Shen Extract (10:1) |
● Dan Shen acts as a platelet activation inhibitor, preventing platelets from contributing to clot formation. (4) ● Salvianolic Acids A and B, the active ingredients in Dan Shen, inhibit platelet activation by inhibiting the P2Y1 and P2Y12 G-Protein Couples Receptors (mechanism of action). (4) ● Salvianolic Acids A and B are also known to be powerful antioxidants and anti-inflammatory agents. (4) |
Organic Beet Root Extract |
● Beet Root extract is a natural means of boosting nitric oxide (NO) production in the body. (5) ● An increase in nitric oxide (NO) helps boost oxygen delivery to the muscles and tissues, which can potentially help alleviate fatigue in Long Covid. (6) ● Nitric oxide (NO) also acts as a platelet activation inhibitor, potentially inhibiting platelet hyperactivation in Long Covid. (6) ● Beet Root extract and the bioactive ingredients it contains are known to be potent antioxidants and anti-inflammatory agents. (6) |
Black Pepper Fruit Extract 95% (Piper nigrum) |
● The active ingredient in Black Pepper Root extract, piperine, boosts the bioavailability and duration of action of Turmeric. (6) ● Piperine inhibits the metabolism of the curcumin active ingredient in Turmeric, increasing both the concentration of curcumin and its duration of action. (6) |
Proper Use of This Supplement |
Suggested Use: As a dietary Supplement, take two (2) capsules with 8-12 fl oz of water. Warning: For use by healthy adults only, not recommended for personas under the age of 18. Do not use if you are pregnant or nursing. Seek advice from a healthcare professional before taking if you have any preexisting medical condition to ensure it is safe to take this product. In case of accidental overdose, contact a poison control center immediately. |
Our Formula vs Other Formulas on the Market |
|
Our Formula |
Other Formulas |
1. Uses third-party independently tested ingredients that are made in the USA, GMP certified and made in an FDA registered facility. |
1. Source cheap ingredients from heavily polluted soils. Even “organic” supplements not third party tested have been removed by FDA due to high levels of heavy metals. |
2. Uses high-quality, organic Turmeric that is 95% curcumin (the active ingredient). |
2. Uses low-quality non-organic Turmeric that is <50 % curcumin (the active ingredient). |
3. Uses high-quality White Willow Extract that’s been standardized to 15% salicin, the active ingredient. |
3. Uses low-quality White Willow Extract with no salicin standardization and low salicin content. |
4. Uses a highly concentrated 10:1 extract of Dan Shen. |
4. Uses small doses of unconcentrated Dan Shen. |
5. Uses high-quality organic Beet Root extract that maximizes NO production, oxygen delivery, and increase of energy and stamina. |
5. Uses low-quality, non-organic beet root with weak NO boosting properties. |
6. Uses Black Pepper extract to boost the bioavailability and duration of action of the curcumin in turmeric. |
6. Does not use Black Pepper extract and has low bioavailability and short duration of action for curcumin. |
Our formula is third party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world class standards.
Sources:
- Laubscher, G. J.; Khan, M. A.; Venter, C.; Pretorius, J. H.; Kell, D. B.; and Pretorius, E. Treatment of Long COVID symptoms with triple anticoagulant therapy. Research Square Preprint2023, rs-2697680/v1. https://doi.org/10.21203/rs.3.rs-2697680/v1
- Kim D.C., Ku S.K., Bae J.S. Anticoagulant activities of curcumin and its derivative. BMB Rep. 2012, 45, 221–226. https://doi.org/10.5483/BMBRep.2012.45.4.221
- Khayyala, M. T.; El-Ghazalyb, M. A.; Abdallaha, D. M.; Okpanyic, S. N.; Kelberc, O.; and Weiserc, D. Mechanisms Involved in the Anti-inflammatory Effect of a Standardized Willow Bark Extract. -Forsch./Drug Res. 2005, 55(11), 677−687. https://doi.org/10.1055/s-0031-1296917
- Liu, X.; Gao, Z.-G.; Wu, Y.; Stevens, R. C.; Jacobson, K. A.; and Zhao, S. Salvianolic acids from antithrombotic Traditional Chinese Medicine Danshen are antagonists of human P2Y1 and P2Y12 receptors. Scientific Rep. 2018, 8, 8084. https://doi.org/10.1038/s41598-018-26577-0
- Clifford, T.; Howatson, G.; West, D. J.; and Stevenson, E. J. The Potential Benefits of Red Beetroot Supplementation in Health and Disease. Nutrients 2015, 7, 2801-2822. https://doi.org/10.3390/nu7042801
- Tabanelli, R.; Brogi, S.; Calderone, V. Improving Curcumin Bioavailability: Current Strategies and Future Perspectives. Pharmaceutics 2021, 13, 1715. https://doi.org/10.3390/pharmaceutics13101715
Has helped my dysautonomia symptoms, headaches, and brain fog associated with long covid. I’ve tried countless supplements to help manage my long covid and this as one of the best I’ve tried.
I've been taking CircuGuard for almost a month now and within the first few days, I just felt kind of miraculously clear-headed. Like the last remaining cognitive fog I had from Long COVID was lifted. This feeling has remained. I started with one pill a day and I am up to four pills per day with no side effects at all. I will take for a few more months to see if the smalls clots I have under my fingernails resolve. I'll update my review if they do. Of all of the many supplements I've tried during my four years of Long COVID, this was the only one where I actually felt a difference. It's definitely worth a try. P.S. my functional medicine doctor reviewed the ingredients and he liked all of them.
I'm a LONG long hauler, and finally found a place to get my blood tested at just over 3 years in - yup: it's full of microclots! The idea of blood thinners and triple anticoagulant therapy concerned me, it feels very high risk living at home alone in an already unstable condition. I'm SO grateful for this all natural alternative, and the cost is WAY lower than the Rx combo my doctors recommended! I'm on my 3rd week of taking CircuGuard daily, with ZERO side effects or reactions, and FINALLY feeling hopeful for a full recovery. I've followed the microclots research, followed Keith's research to create this supplement, and feel confident this is the KEY to getting my life back!
My wife has struggled with Long COVID for nearly two years, and CircuGuard is the only thing that has helped with her fatigue, brain fog, and joint pain! She is finally starting to recover and is getting her life back!